Alkaloids

The chemistry and biochemistry of alkaloids.


Alkaloids are nitrogen containing chemical compounds. They are naturally accuring in a wide range of plants and other organisms (secondary metabolites) and they have often pharmacological effects.

Chemically, the alkaloids organic are chemical compounds that can be structured very differently and exercise quite different functions in nature. A chemical classification is often on hand of the basic molecular structure, such as a particular ring system. Another classification is based on the occurrence in nature of (ergot alkaloids). Biochemically these natural substances are secondary metabolites.

Below you will find information on the chemistry of alkaloids.



Content:


Current Articles
General Information
Special Information
Compound Classes
Nomenclature
Chemical Reactions
Biosyntheses
Metabolism, metabolic pathways



Current Articles


Alkaloid-storing Dwarf Frogs
Poison dwarfs of the Caribbean: Researchers discover skin toxins in the smallest frog of the world

Chemists synthesize herbal alkaloid
Total Synthesis of the Lycopodium Alkaloid (+)-Serratezomine A

The Beaver as Chemist
Total synthesis of enantiomerically pure nupharamine alkaloids from castoreum



General Information


Alkaloid Chemistry: the Work of Walter A. Jacobs
JBC article

Alkaloids
An introduction. Wiley - Format: PDF

Alkaloids
Basics - Format: PDF

Alkaloids
eBook - Format: PDF

Atropine
Basic information

Biosynthesis of Alkaloids
Article - Format: PDF

Plant Alkaloids
An overview - Format: PDF

Pyrrolizidine alkaloids
Chemical Profile for Pyrrolizidine Alkaloids (CAS Number: EDF-168)

Pyrrolizidine alkaloids in food
A Toxicological Review and Risk Assessment - Format: PDF

Sabadilla Alkaloids
Chemical Profile for Sabadilla Alkaloids



Special Information


Research in the chemistry of diterpenoid alkaloids
IUPAC

Resolution, chiral synthesis or what? Studies in alkaloid chemistry
IUPAC



Compound Classes


Acridine Alkaloids
PDF slides - Format: PDF

Indolizidine Alkaloids
Structures and synthesis - Format: PDF

Lupin Alkaloids
Compounds and reactions - Format: PDF

Pyrrole-Imidazole Alkaloids
Compounds and reactions - Format: PDF

Zoanthamine Alkaloids
The biology and chemistry of the zoanthamine alkaloids - Format: PDF



Nomenclature


Nomenclature: Alkaloids
IUPAC

Nomenclature: Natural Products and Related Compounds
IUPAC



Chemical Reactions


Alkaloid Photochemistry
Notes and mechanisms - Format: PDF



Biosyntheses


Acridone alkaloid biosynthesis
Reference pathway. Kegg, Japan

Alkaloid biosynthesis I
Reference pathway. Kegg

Alkaloid biosynthesis II
Reference pathway. Kegg

Biosynthesis of alkaloids
derived from terpenoid and polyketide. Kegg

Biosynthesis of alkaloids
derived from histidine and purine. Kegg

Biosynthesis of alkaloids
derived from shikimate pathway. Kegg

Biosynthesis of alkaloids
derived from ornithine, lysine and nicotinic acid. Kegg

Indole and ipecac alkaloid biosynthesis
Reference pathway. Kegg

The biosynthesis of plant alkaloids
... and nitrogenous microbial metabolites - Format: PDF



Metabolism, metabolic pathways


Caffeine metabolism
Reference pathway. Kegg




Related Books and Scientific Literature: Alkaloids


Book recommendation

Ernesto Fattorusso, Orazio Taglialatela-Scafati

Modern Alkaloids: Structure, Isolation, Synthesis and Biology

This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up to date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis. It is a must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry.

Wiley-VCH; 2007





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Entries: 33

Last update 16.11.2016

Keywords: Alkaloids, chemistry, properties, structures, biochemistry, synthesis





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