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Journal of Medicinal Chemistry - Current Research Articles



Current research articles: Medicinal Chemistry

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Journal of Medicinal Chemistry - Editor: American Chemical Society, ACS

The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.




Current articles of the journal:



3,4-Diaminobenzoic Acid Derivatives as Inhibitors of the Oxytocinase Subfamily of M1 Aminopeptidases with Immune-Regulating Properties

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501867s

Posted on 30 January 2015 | 3:47 pm


Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501755d

Posted on 30 January 2015 | 3:46 pm


Structure–Activity Relationship for the Oxadiazole Class of Antibiotics

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501661f

Posted on 30 January 2015 | 3:37 pm


Discovery and Development of Galeterone (TOK-001 or VN/124-1) for the Treatment of All Stages of Prostate Cancer

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501239f

Posted on 28 January 2015 | 9:40 pm


Function-Oriented Development of CXCR4 Antagonists as Selective Human Immunodeficiency Virus (HIV)-1 Entry Inhibitors

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501772w

Posted on 28 January 2015 | 2:19 pm


2-(2-Oxo-morpholin-3-yl)-acetamide Derivatives as Broad-Spectrum Antifungal Agents

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501814x

Posted on 28 January 2015 | 6:44 am


Glycosylated Enfuvirtide: A Long-Lasting Glycopeptide with Potent Anti-HIV Activity

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5016582

Posted on 27 January 2015 | 9:59 pm


Design, Synthesis, and Biological Evaluation of Combretabenzodiazepines: A Novel Class of Anti-Tubulin Agents

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5016389

Posted on 27 January 2015 | 8:03 pm


Dual Antitumor and Antiangiogenic Activity of Organoplatinum(II) Complexes

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501662b

Posted on 27 January 2015 | 6:12 am


Design, Synthesis, and Biological Evaluation of Sulfonyl Acrylonitriles as Novel Inhibitors of Cancer Metastasis and Spread

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501437v

Posted on 26 January 2015 | 8:47 pm


Discovery of Potent Heterodimeric Antagonists of Inhibitor of Apoptosis Proteins (IAPs) with Sustained Antitumor Activity

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501482t

Posted on 23 January 2015 | 8:36 pm


Novel 3-Nitrotriazole-Based Amides and Carbinols as Bifunctional Antichagasic Agents

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5015742

Posted on 23 January 2015 | 3:05 pm


Antibacterial Drug Leads: DNA and Enzyme Multitargeting

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501449u

Posted on 22 January 2015 | 10:12 pm


Small Molecule Discoidin Domain Receptor Kinase Inhibitors and Potential Medical Applications

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5012319

Posted on 21 January 2015 | 9:36 pm


Exploration of Cyanine Compounds as Selective Inhibitors of Protein Arginine Methyltransferases: Synthesis and Biological Evaluation

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501452j

Posted on 21 January 2015 | 9:36 pm


A High-Throughput Screen Reveals New Small-Molecule Activators and Inhibitors of Pantothenate Kinases

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501585q

Posted on 21 January 2015 | 4:48 pm


Identification of the Minimum Peptide from Mouse Myostatin Prodomain for Human Myostatin Inhibition

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501170d

Posted on 21 January 2015 | 4:47 pm


Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase Open New Prospects for the Treatment of Neurological Disorders

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5b00057

Posted on 20 January 2015 | 9:28 pm


Promiscuous 2-Aminothiazoles (PrATs): A Frequent Hitting Scaffold

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501402x

Posted on 16 January 2015 | 7:14 pm


Design, Synthesis, and Biological Evaluation of Tetrazole Analogs of Cl-Amidine as Protein Arginine Deiminase Inhibitors

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501636x

Posted on 16 January 2015 | 5:42 pm


Stemistry: The Control of Stem Cells in Situ Using Chemistry

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500838d

Posted on 15 January 2015 | 8:04 pm


Computational Methods for Medicinal Chemistry

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5b00053

Posted on 14 January 2015 | 9:13 pm


Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501504k

Posted on 14 January 2015 | 8:44 pm


Highly Selective Salicylketoxime-Based Estrogen Receptor ? Agonists Display Antiproliferative Activities in a Glioma Model

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501829f

Posted on 14 January 2015 | 3:00 pm


Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK)

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5017494

Posted on 14 January 2015 | 2:56 pm


Nintedanib: From Discovery to the Clinic

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501562a

Posted on 14 January 2015 | 2:49 pm


Organic Carbamates in Drug Design and Medicinal Chemistry

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501371s

Posted on 7 January 2015 | 2:38 pm


CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501535r

Posted on 6 January 2015 | 8:55 pm


Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501719e

Posted on 29 December 2014 | 2:00 pm


Targeting DNA Methylation with Small Molecules: What’s Next?

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500843d

Posted on 4 December 2014 | 8:50 pm


Parallel Worlds of Public and Commercial Bioactive Chemistry Data

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5011308

Posted on 4 December 2014 | 6:35 am


Selective Inhibitors of Protein Methyltransferases

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501234a

Posted on 2 December 2014 | 6:22 am


Targeting Aldose Reductase for the Treatment of Diabetes Complications and Inflammatory Diseases: New Insights and Future Directions

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500907a

Posted on 17 November 2014 | 8:47 pm


Inhibiting the Deubiquitinating Enzymes (DUBs)

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501061a

Posted on 14 November 2014 | 8:13 pm


Small-Molecule Inhibitors of the MDM2–p53 Protein–Protein Interaction (MDM2 Inhibitors) in Clinical Trials for Cancer Treatment

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501092z

Posted on 14 November 2014 | 8:12 pm


Glucagon-like Peptide-1 (GLP-1) Analogs: Recent Advances, New Possibilities, and Therapeutic Implications

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500810s

Posted on 13 November 2014 | 12:22 pm





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Chronological list of recent articles on Chemistry, Medicinal Chemistry, Journal of Medicinal Chemistry.
Update:
28.09.2013


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