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Journal of Medicinal Chemistry - Current Research Articles



Current research articles: Medicinal Chemistry

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Journal of Medicinal Chemistry - Editor: American Chemical Society, ACS

The Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.




Current articles of the journal:



Modular Assembly of Purine-like Bisphosphonates as Inhibitors of HIV-1 Reverse Transcriptase

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501010f

Posted on 29 August 2014 | 5:03 pm


Synthetic ?-3 Epoxyfatty Acids As Antiproliferative and Pro-apoptotic Agents in Human Breast Cancer Cells

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501083y

Posted on 29 August 2014 | 2:59 pm


Progress in the Discovery and Development of Heat Shock Protein 90 (Hsp90) Inhibitors

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500823a

Posted on 29 August 2014 | 6:37 am


Small Molecule Adenosine 5?-Monophosphate Activated Protein Kinase (AMPK) Modulators and Human Diseases

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Journal of Medicinal Chemistry
DOI: 10.1021/jm401994c

Posted on 28 August 2014 | 9:44 pm


A New Avenue toward Androgen Receptor Pan-antagonists: C2 Sterically Hindered Substitution of Hydroxy-propanamides

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5005122

Posted on 28 August 2014 | 4:52 pm


Small-Molecule Suppression of ?-Lactam Resistance in Multidrug-Resistant Gram-Negative Pathogens

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Journal of Medicinal Chemistry
DOI: 10.1021/jm501050e

Posted on 28 August 2014 | 4:51 pm


Propylene Cross-Bridged Macrocyclic Bifunctional Chelator: A New Design for Facile Bioconjugation and Robust 64Cu Complex Stability

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500348z

Posted on 26 August 2014 | 8:51 pm


Synthesis, Characterization, and Biological Evaluation of New Ru(II) Polypyridyl Photosensitizers for Photodynamic Therapy

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500566f

Posted on 26 August 2014 | 2:50 pm


Design, Synthesis, and Biological Evaluation of Stable Colchicine Binding Site Tubulin Inhibitors as Potential Anticancer Agents

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500764v

Posted on 26 August 2014 | 6:04 am


The Identification of Perillyl Alcohol Glycosides with Improved Antiproliferative Activity

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500870u

Posted on 25 August 2014 | 5:09 pm


Synthesis and Structure–Activity Relationships of Pteridine Dione and Trione Monocarboxylate Transporter 1 Inhibitors

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500640x

Posted on 22 August 2014 | 8:06 pm


Human Toll-Like Receptor 8-Selective Agonistic Activities in 1-Alkyl-1H-benzimidazol-2-amines

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500701q

Posted on 20 August 2014 | 3:47 pm


Water-Soluble and Cleavable Quercetin–Amino Acid Conjugates as Safe Modulators for P-Glycoprotein-Based Multidrug Resistance

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500290c

Posted on 20 August 2014 | 6:41 am


Rational Use of Plasma Protein and Tissue Binding Data in Drug Design

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5007935

Posted on 6 August 2014 | 7:51 pm


Small Molecule Ghrelin Receptor Inverse Agonists and Antagonists

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5003183

Posted on 6 August 2014 | 2:20 pm


Current Compound Coverage of the Kinome

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5008159

Posted on 30 July 2014 | 8:49 pm


Optimization of Potent DFG-in Inhibitors of Platelet Derived Growth Factor Receptor? (PDGF-R?) Guided by Water Thermodynamics

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500373x

Posted on 21 July 2014 | 9:06 pm


Development of First Lead Structures for Phosphoinositide 3-Kinase-C2? Inhibitors

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5006034

Posted on 14 July 2014 | 3:00 pm


Toward Fluorescent Probes for G-Protein-Coupled Receptors (GPCRs)

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Journal of Medicinal Chemistry
DOI: 10.1021/jm401823z

Posted on 10 July 2014 | 9:01 pm


Targeting the Androgen Receptor with Steroid Conjugates

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500101h

Posted on 8 July 2014 | 6:35 am


Discovery of Selective and Orally Bioavailable Protein Kinase C? (PKC?) Inhibitors from a Fragment Hit

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500669m

Posted on 7 July 2014 | 10:10 pm


Recent Developments in Novel Antidepressants Targeting ?4?2-Nicotinic Acetylcholine Receptors

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Journal of Medicinal Chemistry
DOI: 10.1021/jm401937a

Posted on 2 July 2014 | 10:11 pm


Polypharmacology: Challenges and Opportunities in Drug Discovery

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5006463

Posted on 25 June 2014 | 10:27 pm


Calcitonin Gene-Related Peptide Receptor Antagonists: New Therapeutic Agents for Migraine

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500364u

Posted on 24 June 2014 | 10:26 pm


Development of Synthetic Lethality Anticancer Therapeutics

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500415t

Posted on 13 June 2014 | 8:52 pm


Elements and Modulation of Functional Dynamics

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500325k

Posted on 10 June 2014 | 2:08 pm


Physicochemical Descriptors of Aromatic Character and Their Use in Drug Discovery

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500515d

Posted on 3 June 2014 | 10:51 pm


Serotonin 5-HT6 Receptor Antagonists for the Treatment of Cognitive Deficiency in Alzheimer’s Disease

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Journal of Medicinal Chemistry
DOI: 10.1021/jm5003952

Posted on 3 June 2014 | 7:05 pm


The Medicinal Chemistry of Liver X Receptor (LXR) Modulators

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500442z

Posted on 28 May 2014 | 9:12 pm


Structural Basis for Isoform Selectivity in a Class of Benzothiazole Inhibitors of Phosphoinositide 3-Kinase ?

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Journal of Medicinal Chemistry
DOI: 10.1021/jm500362j

Posted on 2 May 2014 | 12:44 pm





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Chronological list of recent articles on Chemistry, Medicinal Chemistry, Journal of Medicinal Chemistry.
Update:
28.09.2013


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