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Protecting Groups in Chemistry

Protecting Groups

In chemistry a protecting group - or: protective group - is used in synthesis to temporarily mask the characteristic chemistry of a functional group because it interferes with another reaction.

Online available information resources about chemical protecting groups.

Further information categories about related topics are listed in the navigation menu on the left side of these page.

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General Information

Protecting Groups
Amino; Carbonyl; Carboxyl; Hydroxyl (1,2-; 1,3-Diols) - Stability. Organic Chemistry Portal - [e, d]

Protecting Groups
Some protective groups udes in organic synthesis - Format: PDF - [e]

Protecting Groups
Review: protecting group strategies in organic synthesis. Royal Society of Chemistry, UK - [e]

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Lecture Notes, Tutorials

Protecting Groups
A valuable addition to the synthetic chemist's bookshelf. The focus is on a relatively small number of commonly used protecting groups, on deprotecting conditions, and on the extensive use of schemes to aid visual retrieval of information.. Thieme, eBook - [e]

Protecting Groups
... for organic synthesis - Format: PDF - [e]

Silicon-Based Protecting Groups - Format: PDF - [e]

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Special Information

Protecting Groups for Alcohols - Format: PDF - [e]

Alcohols and phenols
Protection of alcohols and phenols with methoxymethyl acetate - [e]

Amino acids
Synthetic protecting groups for amino acids - [e]

Boc-Protected Amino Groups
tert-Butyl carbamates. Organic Chemistry Portal, Switzerland - [e, d]

Protecting groups in carbohydrate chemistry - Format: PDF - [e]

Monohalo Ethers in Protection Chemistry
Applications and mechanisms - [e]

Oxygen-based functionality
Protecting Groups in Organic Chemistry for Oxygen-based functionality - Format: PDF - [e]

Peptide Synthesis
Protecting groups used in peptide synthesis - [e]

Peptide Synthesis
Protecting groups used in peptide synthesis - [e]

Protective Groups
Silicon-Based Protection of Hydroxyl Groups, Esters, Carbonates, Acetals, Ethers, Diols, Carbohydrates, Phenols, Carbonyl Group, Carboxyl Group, Amino Group, Terminal Acetylene - Format: PDF - [e]

Pyrrole Nitrogen
Protecting groups for the pyrrole nitrogen atom. The 2-chloroethyl, 2-phenylsulfonylethyl, and related moieties - Format: PDF - [e]

Urethanes Protecting Groups
Amine protecting groups - [e]

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Data and Databases

Protecting Groups chemical database
Protecting group chemistry data from 1913 onward. Accelrys, USA - [e]

[Gen] [Lec] [Special] [Data] [Diss]



Highly Efficient Photolabile Protecting Groups
with Intramolecular Energy Transfer. University of Konstanz, Germany, 2006 - [e]

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Protecting Groups in Chemistry
Protecting, protective, groups, basic, information, theory, applications, research
22.02.2012 00:00:00 [link check]
22.02.2012 [site update]

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Related Books and Scientific Literature: Protecting Groups:


Peter G. M. Wuts, Theodora W. Greene

Greene's Protective Groups in Organic Synthesis

For more than twenty-five years, Protective Groups in Organic Synthesis has been the definitive guide for organic chemists in designing synthetic routes. Now in its fourth edition, the text continues to be a uniquely comprehensive and an indispensable reference for both synthetic organic and medicinal chemists who want to control the reactivity of the most common functional groups during a synthetic sequence.

The Fourth Edition includes significant developments in protective group chemistry since 1998. In addition to incorporating new protective groups now available to the synthetic organic chemist, such as the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines, the book also covers new techniques for the formation and cleavage of existing protective groups, providing the most relevant and useful examples to illustrate each methodology. The content is organized around the functional group to be protected (ethers, acids, carbonyl groups, amines, amides, phenols, etc.), and ranges from the simplest to the most complex highly specialized protective groups.

Wiley-Interscience; 2006

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