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Acrylamide and Glycidamide


Acrylamide (prop-2-enamide) and glycidamide are organic chemical compounds in the chemical group of amides.

Online available information resources about the chemistry and the toxicology of acrylamide and glycidamide.

Further information categories about related topics are listed in the navigation menu on the left side of these page.

[Gen] [Ana] [Tox] [Med] [Prod]


General Information

Substance profile. NTP, USA - [e]

[Gen] [Ana] [Tox] [Med] [Prod]


Analysis and Determination

Acrylamide Analysis
Two GC-MS Methods for the Analysis of Acrylamide in Foodstuffs - Format: PDF - [e]

Acrylamide Analysis
... by Gas Chromatography. PerkinElmer - Format: PDF - [e]

Acrylamide in Food Samples
Fast Determination of Acrylamide in Food Samples Using Accelerated Solvent Extraction Followed by Ion Chromatography with UV or MS Detection. Dionex, 2003 - Format: PDF - [e]

Analytical Methods
Overview on analytical methods for the determination of acrylamide in food products. JRC, 2003 - Format: PDF - [e]

Determination of Acrylamide
... in Food Simulants. BfR - Format: PDF - [e]

[Gen] [Ana] [Tox] [Med] [Prod]


Toxicology and Medicinal Chemistry

Testing Status. NTP - [e]

Acrylamide Monograph
NTP-CERHR monograph on the potential human reproductive and developmental effects of acrylamide. CERHR, 2005 - [e]

Open access article: The Genotoxicity of Acrylamide and Glycidamide. Journal of the National Cancer Institute 2004 96(13):1023-1029; doi:10.1093/jnci/djh186 - [e]

Testing Status. NTP - [e]

[Gen] [Ana] [Tox] [Med] [Prod]


Medicinal Chemistry

Acrylamide Carcinogenicity
Information site. EFSA, 2008 - [e]

... of acrylamide. EFSA, 2008 - Format: PDF - [e]

[Gen] [Ana] [Tox] [Med] [Prod]


Companies and Products

Acrylamide Kit I
... for the determination of acrylamide acc. to the Grob method. Sigma-Aldrich/Fluka - [e]

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Acrylamide and Glycidamide
Acrylamide, glycidamide, chemistry, toxicology, data, information
07.03.2012 00:00:00 [link check]
07.03.2012 [site update]

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Related Books and Scientific Literature: Acrylamide:


Mendel Friedman, Don Mottram

Chemistry and Safety of Acrylamide in Food

Reports that heat processing of foods induces the formation of acrylamide heightened interest in the chemistry, biochemistry, and safety of this compound. Acrylamide-induced neurotoxicity, reproductive toxicity, genotoxicity, and carcinogenicity are potential human health risks based on animal studies. Because exposure of humans to acrylamide can come from both external sources and the diet, there exists a need to develop a better understanding of its formation and distribution in food and its role in human health. To contribute to this effort, experts from eight countries have presented data on the chemistry, analysis, metabolism, pharmacology, and toxicology of acrylamide.

Specifically covered are the following aspects: exposure from the environment and the diet; biomarkers of exposure; risk assessment; epidemiology; mechanism of formation in food; biological alkylation of amino acids, peptides, proteins, and DNA by acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; protection against adverse effects; and possible approaches to reducing levels in food. Cross-fertilization of ideas among several disciplines in which an interest in acrylamide has developed, including food science, pharmacology, toxicology, and medicine, will provide a better understanding of the chemistry and biology of acrylamide in food, and can lead to the development of food processes to decrease the acrylamide content of the diet.

Springer; 2005

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